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NAR 2026 manuscript: sync M10_results_structure_curation.tex with Overleaf edits #310

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NAR 2026 manuscript: sync M10_results_structure_curation.tex with Overleaf edits #310

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3 changes: 2 additions & 1 deletion Papers/NAR_Update_2026/latex/sections/M10_results_structure_curation.tex
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\subsection{Structure curation}\label{sec:results-structure}

We built and ran our curation pipeline on all structures that would impact the set of roughly 9,000 reactions used in the ModelSEED and PlantSEED reconstruction templates. The conflict pipeline resolved every previously conflicting compound in three curation rounds. i) Instances where the conflict existed at the level of mobile hydrogens were resolved automatically using historical formula ii) instances where the structures were structurally different were resolved manually iii) instances where resolution was not straight-forward were entered in the mass-balance exclusion registry where we fix an arbitrarily chosen formula because no source formula was defensible.
We built and ran our curation pipeline on all structures that would impact the set of roughly 9,000 reactions used in the ModelSEED and PlantSEED reconstruction templates.
The conflict pipeline resolved every previously conflicting compound in a three-staged curation: i) historical formula were used to automatically resolve conflicts in mobile hydrogens; ii) manual curation resolved conflicts in molecular structures; and iii) where steps i-ii fail because of an absence in defensible source formula, reactions were added to a mass-balance exclusion registry where we fix an arbitrarily chosen formula.