diff --git a/packages/dom/src/lib/ElementAssertion.ts b/packages/dom/src/lib/ElementAssertion.ts
index 8207cc9..ca3ce5d 100644
--- a/packages/dom/src/lib/ElementAssertion.ts
+++ b/packages/dom/src/lib/ElementAssertion.ts
@@ -2,7 +2,7 @@ import { Assertion, AssertionError } from "@assertive-ts/core";
 import equal from "fast-deep-equal";
 
 import { getAccessibleDescription, isValidAriaPressed } from "./helpers/accessibility";
-import { isButtonElement, isElementEmpty, normalizeHtml } from "./helpers/dom";
+import { isButtonElement, isElementEmpty, isElementOrAncestorDisabled, normalizeHtml } from "./helpers/dom";
 import { getExpectedAndReceivedStyles } from "./helpers/styles";
 
 export class ElementAssertion<T extends Element> extends Assertion<T> {
@@ -479,6 +479,58 @@ export class ElementAssertion<T extends Element> extends Assertion<T> {
     });
   }
 
+  /**
+   * Asserts that the element is disabled.
+   *
+   * @example
+   * expect(element).toBeDisabled();
+   * expect(element).not.toBeDisabled();
+   *
+   * @returns the assertion instance.
+   */
+  public toBeDisabled(): this {
+    const isDisabled = isElementOrAncestorDisabled(this.actual);
+    const error = new AssertionError({
+      actual: this.actual,
+      message: "Expected the element to be disabled",
+    });
+    const invertedError = new AssertionError({
+      actual: this.actual,
+      message: "Expected the element to NOT be disabled",
+    });
+    return this.execute({
+      assertWhen: isDisabled,
+      error,
+      invertedError,
+    });
+  }
+
+  /**
+   * Asserts that the element is enabled.
+   *
+   * @example
+   * expect(element).toBeEnabled();
+   * expect(element).not.toBeEnabled();
+   *
+   * @returns the assertion instance.
+   */
+  public toBeEnabled(): this {
+    const isEnabled = !isElementOrAncestorDisabled(this.actual);
+    const error = new AssertionError({
+      actual: this.actual,
+      message: "Expected the element to be enabled",
+    });
+    const invertedError = new AssertionError({
+      actual: this.actual,
+      message: "Expected the element to NOT be enabled",
+    });
+    return this.execute({
+      assertWhen: isEnabled,
+      error,
+      invertedError,
+    });
+  }
+
   /**
    * Helper method to assert the presence or absence of class names.
    *
diff --git a/packages/dom/src/lib/helpers/dom.ts b/packages/dom/src/lib/helpers/dom.ts
index 7850bc8..e32cb14 100644
--- a/packages/dom/src/lib/helpers/dom.ts
+++ b/packages/dom/src/lib/helpers/dom.ts
@@ -25,3 +25,56 @@ export function isButtonElement(element: Element): boolean {
 
   return isNativeButton || hasButtonRole;
 }
+
+const FORM_TAGS = [
+  "fieldset",
+  "input",
+  "select",
+  "optgroup",
+  "option",
+  "button",
+  "textarea",
+];
+
+function isFirstLegendChildOfFieldset(element: Element, parent: Element | null): boolean {
+  return (
+    element.tagName.toLowerCase() === "legend"
+    && parent?.tagName.toLowerCase() === "fieldset"
+    && element === Array.from(parent.children).find(child => child.tagName.toLowerCase() === "legend")
+  );
+}
+
+function isElementDisabledByParent(element: Element, parent: Element | null): boolean {
+  return (
+    parent !== null
+    && isElementDisabled(parent) && !isFirstLegendChildOfFieldset(element, parent)
+  );
+}
+
+function isCustomElement(tag: string): boolean {
+  return tag.includes("-");
+}
+
+function canElementBeDisabled(element: Element): boolean {
+  const tag = element.tagName.toLowerCase();
+  return FORM_TAGS.includes(tag) || isCustomElement(tag);
+}
+
+function isElementDisabled(element: Element): boolean {
+  return canElementBeDisabled(element) && element.hasAttribute("disabled");
+}
+
+function isAncestorDisabled(element: Element): boolean {
+  const parent = element.parentElement;
+  return (
+    parent !== null
+    && (isElementDisabledByParent(element, parent) || isAncestorDisabled(parent))
+  );
+}
+
+export function isElementOrAncestorDisabled(element: Element): boolean {
+  return (
+    canElementBeDisabled(element)
+    && (isElementDisabled(element) || isAncestorDisabled(element))
+  );
+}
diff --git a/packages/dom/test/unit/lib/ElementAssertion.test.tsx b/packages/dom/test/unit/lib/ElementAssertion.test.tsx
index 4b101a0..154c6c1 100644
--- a/packages/dom/test/unit/lib/ElementAssertion.test.tsx
+++ b/packages/dom/test/unit/lib/ElementAssertion.test.tsx
@@ -3,6 +3,7 @@ import { render } from "@testing-library/react";
 
 import { ElementAssertion } from "../../../src/lib/ElementAssertion";
 
+import { DisabledTestComponent } from "./fixtures/DisabledTestComponent";
 import { HaveClassTest } from "./fixtures/HaveClassTest";
 import { NestedElementsTest } from "./fixtures/NestedElementsTest";
 import { PressedTestComponent } from "./fixtures/PressedTestComponent";
@@ -904,4 +905,87 @@ describe("[Unit] ElementAssertion.test.ts", () => {
       });
     });
   });
+
+  describe(".toBeDisabled", () => {
+    context("when the element is disabled", () => {
+      it("returns the assertion instance", () => {
+        const { getByTestId } = render(<DisabledTestComponent />);
+
+        const buttonDisabled = getByTestId("button-disabled");
+        expect(new ElementAssertion(buttonDisabled).toBeDisabled()).toBeInstanceOf(ElementAssertion);
+
+        const inputDisabled = getByTestId("input-disabled");
+        expect(new ElementAssertion(inputDisabled).toBeDisabled()).toBeInstanceOf(ElementAssertion);
+
+        const customDisabled = getByTestId("custom-disabled");
+        expect(new ElementAssertion(customDisabled).toBeDisabled()).toBeInstanceOf(ElementAssertion);
+
+        const fieldsetChildDisabled = getByTestId("fieldset-child-disabled");
+        expect(new ElementAssertion(fieldsetChildDisabled).toBeDisabled()).toBeInstanceOf(ElementAssertion);
+
+        const fieldsetLegendSecondChildDisabled = getByTestId("fieldset-legend-second-child-disabled");
+        expect(new ElementAssertion(fieldsetLegendSecondChildDisabled).toBeDisabled()).toBeInstanceOf(ElementAssertion);
+
+        const fieldsetNestedChildDisabled = getByTestId("fieldset-nested-child-disabled");
+        expect(new ElementAssertion(fieldsetNestedChildDisabled).toBeDisabled()).toBeInstanceOf(ElementAssertion);
+      });
+    });
+
+    context("when the element is not disabled", () => {
+      it("throws an assertion error", () => {
+        const { getByTestId } = render(<DisabledTestComponent />);
+
+        const buttonEnabled = getByTestId("button-enabled");
+        const test = new ElementAssertion(buttonEnabled);
+
+        expect(() => test.toBeDisabled())
+          .toThrowError(AssertionError)
+          .toHaveMessage("Expected the element to be disabled");
+        expect(test.not.toBeDisabled()).toBeEqual(test);
+
+        const divDisabled = getByTestId("div-disabled");
+        const testDiv = new ElementAssertion(divDisabled);
+        expect(() => testDiv.toBeDisabled())
+          .toThrowError(AssertionError)
+          .toHaveMessage("Expected the element to be disabled");
+
+        const fieldsetLegendFirstChild = getByTestId("fieldset-legend-first-child");
+        const testLegendFirstChild = new ElementAssertion(fieldsetLegendFirstChild);
+        expect(() => testLegendFirstChild.toBeDisabled())
+          .toThrowError(AssertionError)
+          .toHaveMessage("Expected the element to be disabled");
+      });
+    });
+  });
+
+  describe(".toBeEnabled", () => {
+    context("when the element is enabled", () => {
+      it("returns the assertion instance", () => {
+        const { getByTestId } = render(<DisabledTestComponent />);
+
+        const buttonEnabled = getByTestId("button-enabled");
+        expect(new ElementAssertion(buttonEnabled).toBeEnabled()).toBeInstanceOf(ElementAssertion);
+
+        const divDisabled = getByTestId("div-disabled");
+        expect(new ElementAssertion(divDisabled).toBeEnabled()).toBeInstanceOf(ElementAssertion);
+
+        const fieldsetLegendFirstChild = getByTestId("fieldset-legend-first-child");
+        expect(new ElementAssertion(fieldsetLegendFirstChild).toBeEnabled()).toBeInstanceOf(ElementAssertion);
+      });
+    });
+
+    context("when the element is not enabled", () => {
+      it("throws an assertion error", () => {
+        const { getByTestId } = render(<DisabledTestComponent />);
+
+        const buttonDisabled = getByTestId("button-disabled");
+        const test = new ElementAssertion(buttonDisabled);
+
+        expect(() => test.toBeEnabled())
+          .toThrowError(AssertionError)
+          .toHaveMessage("Expected the element to be enabled");
+        expect(test.not.toBeEnabled()).toBeEqual(test);
+      });
+    });
+  });
 });
diff --git a/packages/dom/test/unit/lib/fixtures/DisabledTestComponent.tsx b/packages/dom/test/unit/lib/fixtures/DisabledTestComponent.tsx
new file mode 100644
index 0000000..3da8c53
--- /dev/null
+++ b/packages/dom/test/unit/lib/fixtures/DisabledTestComponent.tsx
@@ -0,0 +1,29 @@
+import type { ReactElement } from "react";
+
+export function DisabledTestComponent(): ReactElement {
+  return (
+    <div>
+      <button data-testid="button-disabled" disabled={true}>{"Disabled"}</button>
+      <button data-testid="button-enabled">{"Enabled"}</button>
+      <input data-testid="input-disabled" disabled={true} />
+
+      <div data-testid="div-disabled" {...{ disabled: true }}>{"Div Disabled"}</div>
+
+      {/* @ts-expect-error - Custom element */}
+      <custom-element data-testid="custom-disabled" disabled={true} />
+
+      <fieldset data-testid="fieldset-disabled" disabled={true}>
+        <button data-testid="fieldset-child-disabled">{"Disabled child"}</button>
+        <legend>
+          <button data-testid="fieldset-legend-first-child">{"Enabled child in first legend"}</button>
+        </legend>
+        <legend>
+          <button data-testid="fieldset-legend-second-child-disabled">{"Disabled child in second legend"}</button>
+        </legend>
+        <div>
+          <button data-testid="fieldset-nested-child-disabled">{"Nested disabled child"}</button>
+        </div>
+      </fieldset>
+    </div>
+  );
+}