diff --git a/resources/python/bin/3.10/explicit_requirements.txt b/resources/python/bin/3.10/explicit_requirements.txt
index 16bc8dba3..6fd1622e6 100644
--- a/resources/python/bin/3.10/explicit_requirements.txt
+++ b/resources/python/bin/3.10/explicit_requirements.txt
@@ -9,5 +9,5 @@
 # agreement to the Shotgun Pipeline Toolkit Source Code License. All rights
 # not expressly granted therein are reserved by Shotgun Software Inc.
 cffi==2.0.0
-cryptography==46.0.7
+cryptography==48.0.1
 zope.interface==8.3
diff --git a/resources/python/bin/3.11/explicit_requirements.txt b/resources/python/bin/3.11/explicit_requirements.txt
index 16bc8dba3..6fd1622e6 100644
--- a/resources/python/bin/3.11/explicit_requirements.txt
+++ b/resources/python/bin/3.11/explicit_requirements.txt
@@ -9,5 +9,5 @@
 # agreement to the Shotgun Pipeline Toolkit Source Code License. All rights
 # not expressly granted therein are reserved by Shotgun Software Inc.
 cffi==2.0.0
-cryptography==46.0.7
+cryptography==48.0.1
 zope.interface==8.3
diff --git a/resources/python/bin/3.13/explicit_requirements.txt b/resources/python/bin/3.13/explicit_requirements.txt
index 16bc8dba3..6fd1622e6 100644
--- a/resources/python/bin/3.13/explicit_requirements.txt
+++ b/resources/python/bin/3.13/explicit_requirements.txt
@@ -9,5 +9,5 @@
 # agreement to the Shotgun Pipeline Toolkit Source Code License. All rights
 # not expressly granted therein are reserved by Shotgun Software Inc.
 cffi==2.0.0
-cryptography==46.0.7
+cryptography==48.0.1
 zope.interface==8.3
diff --git a/resources/python/bin/3.7/explicit_requirements.txt b/resources/python/bin/3.7/explicit_requirements.txt
index 9b41ea367..633b62309 100644
--- a/resources/python/bin/3.7/explicit_requirements.txt
+++ b/resources/python/bin/3.7/explicit_requirements.txt
@@ -9,5 +9,5 @@
 # agreement to the Shotgun Pipeline Toolkit Source Code License. All rights
 # not expressly granted therein are reserved by Shotgun Software Inc.
 cffi==1.15.1
-cryptography==44.0.3
+cryptography==48.0.1
 zope.interface==6.4.post2
diff --git a/resources/python/bin/3.9/explicit_requirements.txt b/resources/python/bin/3.9/explicit_requirements.txt
index daade2154..b5e7f1760 100644
--- a/resources/python/bin/3.9/explicit_requirements.txt
+++ b/resources/python/bin/3.9/explicit_requirements.txt
@@ -9,5 +9,5 @@
 # agreement to the Shotgun Pipeline Toolkit Source Code License. All rights
 # not expressly granted therein are reserved by Shotgun Software Inc.
 cffi==2.0.0
-cryptography==46.0.7
+cryptography==48.0.1
 zope.interface==8.0.1