diff --git a/packages/react-native/Libraries/StyleSheet/__tests__/processTransformOrigin-itest.js b/packages/react-native/Libraries/StyleSheet/__tests__/processTransformOrigin-itest.js
index 81a882f4175a..318b3f9e088d 100644
--- a/packages/react-native/Libraries/StyleSheet/__tests__/processTransformOrigin-itest.js
+++ b/packages/react-native/Libraries/StyleSheet/__tests__/processTransformOrigin-itest.js
@@ -122,5 +122,16 @@ describe('processTransformOrigin', () => {
       expect(processTransformOrigin('12.5px 7.5px')).toEqual([12.5, 7.5, 0]);
       expect(processTransformOrigin('.5% .5px')).toEqual(['.5%', 0.5, 0]);
     });
+    it('should preserve negative percentage and pixel values', () => {
+      expect(processTransformOrigin('-50.5% -30.2%')).toEqual([
+        '-50.5%',
+        '-30.2%',
+        0,
+      ]);
+      expect(processTransformOrigin('-12.5px -7.5px -2.5px')).toEqual([
+        -12.5, -7.5, -2.5,
+      ]);
+      expect(processTransformOrigin('-.5% -.5px')).toEqual(['-.5%', -0.5, 0]);
+    });
   });
 });
diff --git a/packages/react-native/Libraries/StyleSheet/processTransformOrigin.js b/packages/react-native/Libraries/StyleSheet/processTransformOrigin.js
index 96cd040d8142..5c132d92ae43 100644
--- a/packages/react-native/Libraries/StyleSheet/processTransformOrigin.js
+++ b/packages/react-native/Libraries/StyleSheet/processTransformOrigin.js
@@ -12,7 +12,7 @@ import invariant from 'invariant';
 
 // Pre-compiled regex pattern for performance - avoids regex compilation on each call
 const TRANSFORM_ORIGIN_REGEX =
-  /(top|bottom|left|right|center|\d*\.?\d+(?:%|px)|0)/gi;
+  /(top|bottom|left|right|center|-?\d*\.?\d+(?:%|px)|0)/gi;
 
 const INDEX_X = 0;
 const INDEX_Y = 1;