diff --git a/tests/conftest.py b/tests/conftest.py
index 2fcd4c1..40dcd0d 100644
--- a/tests/conftest.py
+++ b/tests/conftest.py
@@ -140,6 +140,45 @@ def skip(rel_id):
                 # hangs on 3.11+, fails without hanging on 3.8-3.10
                 skip("test_windows_events.py::ProactorLoopCtrlC::test_ctrl_c")
 
+        if sys.platform == "darwin":
+            # These time out on GitHub Actions, unclear why -- possibly an
+            # interaction with macOS safety features for stopping processes
+            # from accessing the network without permissions. They pass fine
+            # on a local machine.
+            for kind in ("Kqueue", "Poll", "Select"):
+                for what in (
+                    "create_connection",
+                    "create_connection_local_addr",
+                    "create_connection_local_addr_in_use",
+                    "create_ssl_connection",
+                    # This one seems to nondeterministically raise ResourceWarnings
+                    "create_server_ssl_verify_failed",
+                ):
+                    skip(f"test_events.py::{kind}EventLoopTests::test_{what}")
+                for what in (
+                    "create_connection_sock",
+                    "huge_content",
+                    "huge_content_recvinto",
+                    "sock_client_connect_racing",
+                    "sock_client_ops",
+                    "sock_client_racing",
+                ):
+                    skip(f"test_sock_lowlevel.py::{kind}EventLoopTests::test_{what}")
+            for what in (
+                "async_writer_api",
+                "async_writer_api_exception_after_close",
+                "eof_feed_when_closing_writer",
+                "loop_is_closed_resource_warnings",
+                "open_connection",
+                "open_connection_error",
+                "open_connection_happy_eyeball_refcycles",
+                "open_connection_no_loop_ssl",
+                "unclosed_resource_warnings",
+                "wait_closed_on_close",
+                "wait_closed_on_close_with_unread_data",
+            ):
+                skip(f"test_streams.py::StreamTests::test_{what}")
+
         if sys.implementation.name == "pypy":
             # This test depends on the C implementation of asyncio.Future, and
             # unlike most such tests it is not configured to be skipped if
@@ -199,12 +238,28 @@ def skip(rel_id):
             xfail(
                 "test_futures2.py::PyFutureTests::test_task_exc_handler_correct_context"
             )
-            xfail(
-                "test_futures2.py::CFutureTests::test_task_exc_handler_correct_context"
-            )
+            if sys.version_info < (3, 13):
+                xfail(
+                    "test_futures2.py::CFutureTests::test_task_exc_handler_correct_context"
+                )
 
             # This test assumes that get_event_loop_policy().get_event_loop() doesn't
             # automatically return the running loop
             skip(
                 "test_subprocess.py::GenericWatcherTests::test_create_subprocess_with_pidfd"
             )
+
+        if sys.version_info >= (3, 13):
+            if sys.platform == "win32":
+                for which in ("read", "write", "read_write"):
+                    # These use a facility of the ProactorEventLoop that
+                    # trio-asyncio doesn't support
+                    xfail(
+                        "test_subprocess.py::SubprocessProactorTests::"
+                        f"test_subprocess_{which}_pipe_cancelled"
+                    )
+            # Fails nondeterministically - unclear issue
+            skip(
+                "test_tasks.py::RunCoroutineThreadsafeTests::"
+                "test_run_coroutine_threadsafe_and_cancel"
+            )
diff --git a/tests/interop/test_calls.py b/tests/interop/test_calls.py
index 59c0197..e090569 100644
--- a/tests/interop/test_calls.py
+++ b/tests/interop/test_calls.py
@@ -299,7 +299,7 @@ async def cancel_trio(seen):
                 seen.flag |= 8
 
         seen = Seen()
-        with trio.testing.RaisesGroup(asyncio.CancelledError):
+        with pytest.RaisesGroup(asyncio.CancelledError):
             await cancel_trio(seen)
         assert seen.flag == 1 | 8
 
diff --git a/tests/test_misc.py b/tests/test_misc.py
index 0c178eb..be83b04 100644
--- a/tests/test_misc.py
+++ b/tests/test_misc.py
@@ -225,7 +225,7 @@ async def run_asyncio_loop(nursery, *, task_status=trio.TASK_STATUS_IGNORED):
     import signal
     import threading
 
-    with trio.testing.RaisesGroup(KeyboardInterrupt):
+    with pytest.RaisesGroup(KeyboardInterrupt):
         async with trio.open_nursery() as nursery:
             await nursery.start(run_asyncio_loop, nursery)
             # Trigger KeyboardInterrupt that should propagate accross the coroutines
@@ -270,7 +270,7 @@ async def trio_task():
         scope.cancel()
     assert fut.done()
     if throw_another:
-        with trio.testing.RaisesGroup(trio.testing.Matcher(ValueError, match="hi")):
+        with pytest.RaisesGroup(pytest.RaisesExc(ValueError, match="hi")):
             fut.result()
     else:
         assert fut.cancelled()
@@ -333,9 +333,9 @@ def collect_exceptions(loop, context):
     )
     expected = [ValueError("hi"), ValueError("lo"), KeyError(), IndexError()]
     await raise_in_aio_loop(expected[0])
-    with trio.testing.RaisesGroup(SystemExit, flatten_subgroups=True):
+    with pytest.RaisesGroup(SystemExit, flatten_subgroups=True):
         await raise_in_aio_loop(SystemExit(0))
-    with trio.testing.RaisesGroup(SystemExit, flatten_subgroups=True) as result:
+    with pytest.RaisesGroup(SystemExit, flatten_subgroups=True) as result:
         await raise_in_aio_loop(BaseExceptionGroup("", [expected[1], SystemExit()]))
 
     assert len(result.value.exceptions) == 1
diff --git a/tests/test_trio_asyncio.py b/tests/test_trio_asyncio.py
index dfbb7e5..7e80029 100644
--- a/tests/test_trio_asyncio.py
+++ b/tests/test_trio_asyncio.py
@@ -123,8 +123,8 @@ async def test_cancel_loop_with_tasks(autojump_clock, shield, body_raises):
     record = []
 
     if body_raises:
-        catcher = trio.testing.RaisesGroup(
-            trio.testing.Matcher(ValueError, match="hi"), flatten_subgroups=True
+        catcher = pytest.RaisesGroup(
+            pytest.RaisesExc(ValueError, match="hi"), flatten_subgroups=True
         )
     else:
         catcher = contextlib.nullcontext()