diff --git a/changelog/13453.improvement.rst b/changelog/13453.improvement.rst
new file mode 100644
index 00000000000..5cc25784c94
--- /dev/null
+++ b/changelog/13453.improvement.rst
@@ -0,0 +1 @@
+When ``BdbQuit`` is raised during a pdb debugging session -- for example when a test directly raises it or when quitting pdb on Python versions older than 3.14 -- pytest now fails the current test and stops the entire test run. Previously the session would continue after ``BdbQuit``, silently skipping teardown. Note: on Python 3.14+ the pdb "quit" path calls ``os._exit(0)`` instead of raising ``BdbQuit``, which pytest cannot intercept -- by :user:`EternalRights`
diff --git a/src/_pytest/runner.py b/src/_pytest/runner.py
index 3f03cfaff77..da4dff77e90 100644
--- a/src/_pytest/runner.py
+++ b/src/_pytest/runner.py
@@ -252,6 +252,10 @@ def call_and_report(
         reraise=get_reraise_exceptions(item.config),
     )
     report: TestReport = ihook.pytest_runtest_makereport(item=item, call=call)
+    # A BdbQuit (e.g. from Ctrl+D in pdb) should stop the session, not just
+    # fail the current test. See #13453.
+    if call.excinfo is not None and isinstance(call.excinfo.value, bdb.BdbQuit):
+        item.session.shouldstop = "Debugger quit (BdbQuit)"
     if log:
         ihook.pytest_runtest_logreport(report=report)
     if check_interactive_exception(call, report):
diff --git a/testing/test_debugging.py b/testing/test_debugging.py
index 950386a4923..07505dc0dcb 100644
--- a/testing/test_debugging.py
+++ b/testing/test_debugging.py
@@ -1376,10 +1376,15 @@ def do_quit(self, *args):
 
 @pytest.mark.xfail(
     sys.version_info >= (3, 14),
-    reason="C-D now quits the test session, rather than failing the test. See https://github.com/python/cpython/issues/124703",
+    reason=(
+        "Python 3.14+ pdb calls os._exit(0) on quit instead of raising "
+        "BdbQuit, so pytest never sees the exception and cannot set "
+        "shouldstop. The fix in call_and_report handles BdbQuit raised "
+        "directly, but os._exit cannot be intercepted."
+    ),
 )
 def test_raises_bdbquit_with_eoferror(pytester: Pytester) -> None:
-    """It is not guaranteed that DontReadFromInput's read is called."""
+    """BdbQuit from Ctrl+D / EOFError should fail the current test and stop the session."""
     p1 = pytester.makepyfile(
         """
         def input_without_read(*args, **kwargs):
@@ -1389,12 +1394,15 @@ def test(monkeypatch):
             import builtins
             monkeypatch.setattr(builtins, "input", input_without_read)
             __import__('pdb').set_trace()
+
+        def test_after_bdbquit():
+            # This test should not run because BdbQuit stops the session.
+            pass
         """
     )
     result = pytester.runpytest(str(p1))
-    result.assert_outcomes(failed=1)
-    result.stdout.fnmatch_lines(["E *BdbQuit", "*= 1 failed in*"])
-    assert result.ret == 1
+    result.stdout.fnmatch_lines(["E *BdbQuit", "*Interrupted: Debugger quit*"])
+    assert result.ret == 2
 
 
 def test_pdb_wrapper_class_is_reused(pytester: Pytester) -> None:
diff --git a/testing/test_unittest.py b/testing/test_unittest.py
index 20287d12cb3..5da14cbfc9a 100644
--- a/testing/test_unittest.py
+++ b/testing/test_unittest.py
@@ -1225,7 +1225,8 @@ def test_should_not_run(self):
     """
     )
     reprec = pytester.inline_run()
-    reprec.assertoutcome(failed=1, passed=1)
+    # BdbQuit now stops the session, so test_should_not_run doesn't run.
+    reprec.assertoutcome(failed=1)
 
 
 def test_exit_outcome(pytester: Pytester) -> None: