diff --git a/autotest/test_mp7_disv_issue_2612.py b/autotest/test_mp7_disv_issue_2612.py
new file mode 100644
index 000000000..043c2c38d
--- /dev/null
+++ b/autotest/test_mp7_disv_issue_2612.py
@@ -0,0 +1,236 @@
+"""
+Tests for issue #2612: MODPATH 7 izone/zones handling on DISV grids.
+"""
+
+import numpy as np
+import pandas as pd
+import pytest
+
+from autotest.test_grid_cases import GridCases
+from flopy.mf6 import (
+    MFSimulation,
+    ModflowEms,
+    ModflowGwf,
+    ModflowGwfchd,
+    ModflowGwfdisv,
+    ModflowGwfic,
+    ModflowGwfnpf,
+    ModflowGwfoc,
+    ModflowIms,
+    ModflowPrt,
+    ModflowPrtdisv,
+    ModflowPrtfmi,
+    ModflowPrtmip,
+    ModflowPrtoc,
+    ModflowPrtprp,
+    ModflowTdis,
+)
+from flopy.modpath import Modpath7, Modpath7Bas, Modpath7Sim, ParticleGroup
+from flopy.modpath.mp7particledata import ParticleData
+from flopy.utils.modpathfile import EndpointFile
+
+SOURCE_CELL = 1
+JUNCTION_CELL = 2
+SINK_CELL = 4
+SOURCE_HEAD = 8.0
+SINK_HEAD = 6.0
+STOPZONE = 2
+
+
+def build_gwf_sim(name, ws):
+    grid = GridCases.vertex_small()
+    sim = MFSimulation(sim_name=name, version="mf6", exe_name="mf6", sim_ws=ws)
+    ModflowTdis(sim, time_units="DAYS", nper=1, perioddata=[(1.0, 1, 1.0)])
+    ModflowIms(
+        sim,
+        complexity="SIMPLE",
+        outer_dvclose=1e-6,
+        outer_maximum=200,
+        inner_dvclose=1e-7,
+        inner_maximum=200,
+    )
+    gwf = ModflowGwf(sim, modelname=name, save_flows=True)
+    ModflowGwfdisv(
+        gwf,
+        nlay=grid.nlay,
+        ncpl=grid.ncpl,
+        nvert=grid.nvert,
+        vertices=grid._vertices,
+        cell2d=grid.cell2d,
+        top=grid.top,
+        botm=grid.botm,
+    )
+    # k33 near zero decouples the layers vertically, so flow (and the
+    # tracked particle) stay in layer 0 where the zones are defined
+    ModflowGwfnpf(
+        gwf,
+        k=1.0,
+        k33=1e-3,
+        save_flows=True,
+        save_specific_discharge=True,
+        save_saturation=True,
+    )
+    ModflowGwfic(gwf, strt=7.0)
+    ModflowGwfchd(
+        gwf,
+        stress_period_data=[
+            [(0, SOURCE_CELL), SOURCE_HEAD],
+            [(0, SINK_CELL), SINK_HEAD],
+        ],
+    )
+    ModflowGwfoc(
+        gwf,
+        budget_filerecord=f"{name}.cbc",
+        head_filerecord=f"{name}.hds",
+        saverecord=[("HEAD", "ALL"), ("BUDGET", "ALL")],
+    )
+    return sim, grid
+
+
+def make_zones(grid, shape):
+    zones2d = np.ones((grid.nlay, grid.ncpl), dtype=np.int32)
+    zones2d[0, JUNCTION_CELL] = STOPZONE
+    if shape == "2d":
+        return zones2d
+    elif shape == "3d":
+        return np.expand_dims(zones2d, axis=1)
+    raise ValueError(shape)
+
+
+def make_particle_data():
+    # node 1 == (layer 0, cell2d SOURCE_CELL), 0-based
+    return ParticleData(
+        partlocs=[SOURCE_CELL],
+        structured=False,
+        localx=[0.5],
+        localy=[0.5],
+        localz=[0.5],
+        drape=0,
+    )
+
+
+@pytest.mark.parametrize("shape", ["2d", "3d"])
+def test_mp7_disv_zones(function_tmpdir, shape):
+    gwf_name = "gwf"
+    sim, grid = build_gwf_sim(gwf_name, function_tmpdir / "mf6")
+    sim.write_simulation()
+    success, buff = sim.run_simulation()
+    assert success, buff
+
+    mp7_ws = function_tmpdir / "mp7"
+    gwf = sim.get_model()
+    mp7 = Modpath7(modelname="mp7", flowmodel=gwf, model_ws=mp7_ws, exe_name="mp7")
+    Modpath7Bas(mp7)
+    Modpath7Sim(
+        mp7,
+        simulationtype="pathline",
+        trackingdirection="forward",
+        weaksinkoption="stop_at",
+        zonedataoption="on",
+        stopzone=STOPZONE,
+        zones=make_zones(grid, shape),
+        particlegroups=[ParticleGroup(particledata=make_particle_data())],
+    )
+    mp7.write_input()
+    success, buff = mp7.run_model()
+    assert success, buff
+
+    ep = EndpointFile(mp7_ws / "mp7.mpend").get_data()
+    assert len(ep) == 1
+    assert ep["k"][0] == 0
+    assert ep["node"][0] == JUNCTION_CELL
+    assert ep["zone"][0] == STOPZONE
+
+
+def test_mp7_disv_zones_2d_3d_equivalent(function_tmpdir):
+    sim, grid = build_gwf_sim("gwf", function_tmpdir / "mf6")
+    gwf = sim.get_model()
+
+    def zones_array_for(shape):
+        mp7 = Modpath7(
+            modelname="mp7",
+            flowmodel=gwf,
+            model_ws=function_tmpdir / f"mp7_{shape}",
+            exe_name="mp7",
+        )
+        Modpath7Bas(mp7)
+        mp7sim = Modpath7Sim(
+            mp7,
+            zonedataoption="on",
+            stopzone=STOPZONE,
+            zones=make_zones(grid, shape),
+            particlegroups=[ParticleGroup(particledata=make_particle_data())],
+        )
+        return mp7sim.zones.array
+
+    np.testing.assert_array_equal(zones_array_for("2d"), zones_array_for("3d"))
+
+
+def test_prt_disv_zones(function_tmpdir):
+    gwf_name = "gwf"
+    mf6_ws = function_tmpdir / "mf6"
+    gwf_sim, grid = build_gwf_sim(gwf_name, mf6_ws)
+    gwf_sim.write_simulation()
+    success, buff = gwf_sim.run_simulation()
+    assert success, buff
+    gwf = gwf_sim.get_model()
+
+    prt_name = "prt"
+    prt_ws = function_tmpdir / "prt"
+    prt_sim = MFSimulation(
+        sim_name=prt_name, version="mf6", exe_name="mf6", sim_ws=prt_ws
+    )
+    ModflowTdis(prt_sim, time_units="DAYS", nper=1, perioddata=[(1.0, 1, 1.0)])
+    prt = ModflowPrt(prt_sim, modelname=prt_name)
+    ModflowPrtdisv(
+        prt,
+        nlay=grid.nlay,
+        ncpl=grid.ncpl,
+        nvert=grid.nvert,
+        vertices=grid._vertices,
+        cell2d=grid.cell2d,
+        top=grid.top,
+        botm=grid.botm,
+    )
+
+    izone = np.ones((grid.nlay, grid.ncpl), dtype=np.int32)
+    izone[0, JUNCTION_CELL] = STOPZONE
+    ModflowPrtmip(prt, porosity=0.3, izone=izone)
+
+    releasepts = list(make_particle_data().to_prp(gwf.modelgrid))
+    ModflowPrtprp(
+        prt,
+        nreleasepts=len(releasepts),
+        packagedata=releasepts,
+        perioddata={0: ["FIRST"]},
+        istopzone=STOPZONE,
+        coordinate_check_method=None,
+    )
+    ModflowPrtoc(
+        prt,
+        budget_filerecord=f"{prt_name}.bud",
+        track_filerecord=f"{prt_name}.trk",
+        trackcsv_filerecord=f"{prt_name}.trk.csv",
+        saverecord=[("BUDGET", "ALL")],
+    )
+    ModflowPrtfmi(
+        prt,
+        packagedata=[
+            ("GWFHEAD", f"../{mf6_ws.name}/{gwf_name}.hds"),
+            ("GWFBUDGET", f"../{mf6_ws.name}/{gwf_name}.cbc"),
+        ],
+    )
+    ems = ModflowEms(prt_sim, filename=f"{prt_name}.ems")
+    prt_sim.register_solution_package(ems, [prt.name])
+
+    prt_sim.write_simulation()
+    success, buff = prt_sim.run_simulation()
+    assert success, buff
+
+    trk = pd.read_csv(prt_ws / f"{prt_name}.trk.csv")
+    term = trk[trk.ireason == 3]  # termination event
+    assert len(term) == 1
+    # 1-based layer/cell2d indices in the PRT track file
+    assert term.iloc[0]["ilay"] == 1
+    assert term.iloc[0]["icell"] == JUNCTION_CELL + 1
+    assert term.iloc[0]["izone"] == STOPZONE
diff --git a/flopy/utils/modpathfile.py b/flopy/utils/modpathfile.py
index 5a34175d5..6c7715256 100644
--- a/flopy/utils/modpathfile.py
+++ b/flopy/utils/modpathfile.py
@@ -532,8 +532,6 @@ class EndpointFile(ModpathFile):
         "particleid",
         "particlegroup",
         "particleidloc",
-        "zone0",
-        "zone",
     ]
 
     def __init__(self, filename: Union[str, PathLike], verbose: bool = False):