diff --git a/pyproject.toml b/pyproject.toml
index 707fa3d..9d11713 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -25,7 +25,7 @@ dependencies = [
     "transformations",
     "etils",
     "einops",
-    "protobuf<4"  # Necessary to avoid "TypeError: Descriptors cannot not be created directly"
+    "protobuf<5"  # Necessary to avoid "TypeError: Descriptors cannot not be created directly"
 ]
 
 # This is set automatically by flit using `diffren.__version__`
diff --git a/third_party/requirements.in b/third_party/requirements.in
index 2ac69a6..a5ffdcf 100644
--- a/third_party/requirements.in
+++ b/third_party/requirements.in
@@ -10,5 +10,5 @@ scikit-image
 transformations
 etils
 einops
-protobuf<4
+protobuf<5
 importlib-resources