diff --git a/dev-packages/deno-integration-tests/suites/orchestrion-express/test.ts b/dev-packages/deno-integration-tests/suites/orchestrion-express/test.ts
new file mode 100644
index 000000000000..1e29b96b5314
--- /dev/null
+++ b/dev-packages/deno-integration-tests/suites/orchestrion-express/test.ts
@@ -0,0 +1,100 @@
+// <reference lib="deno.ns" />
+
+import { EventEmitter } from 'node:events';
+import { tracingChannel } from 'node:diagnostics_channel';
+import type { TransactionEvent } from '@sentry/core';
+import type { DenoClient } from '@sentry/deno';
+import { getCurrentScope, getGlobalScope, getIsolationScope, init, startSpan } from '@sentry/deno';
+import { assert } from 'https://deno.land/std@0.212.0/assert/assert.ts';
+import { assertEquals } from 'https://deno.land/std@0.212.0/assert/assert_equals.ts';
+import { assertExists } from 'https://deno.land/std@0.212.0/assert/assert_exists.ts';
+
+function resetGlobals(): void {
+  getCurrentScope().clear();
+  getCurrentScope().setClient(undefined);
+  getIsolationScope().clear();
+  getGlobalScope().clear();
+}
+
+/** See deno-redis.test.ts — same sink shape, deduped for clarity. */
+function transactionSink(): {
+  beforeSendTransaction: (event: TransactionEvent) => null;
+  waitFor: (predicate: (event: TransactionEvent) => boolean) => Promise<TransactionEvent>;
+} {
+  const transactions: TransactionEvent[] = [];
+  const waiters: { predicate: (e: TransactionEvent) => boolean; resolve: (e: TransactionEvent) => void }[] = [];
+  return {
+    beforeSendTransaction(event) {
+      transactions.push(event);
+      for (let i = waiters.length - 1; i >= 0; i--) {
+        const w = waiters[i]!;
+        if (w.predicate(event)) {
+          waiters.splice(i, 1);
+          w.resolve(event);
+        }
+      }
+      return null;
+    },
+    waitFor(predicate) {
+      const already = transactions.find(predicate);
+      if (already) return Promise.resolve(already);
+      return new Promise<TransactionEvent>(resolve => {
+        waiters.push({ predicate, resolve });
+      });
+    },
+  };
+}
+
+function withTimeout<T>(p: Promise<T>, ms: number, what: string): Promise<T> {
+  let timer: ReturnType<typeof setTimeout> | undefined;
+  const timeout = new Promise<T>((_, reject) => {
+    timer = setTimeout(() => reject(new Error(`Timed out waiting for ${what} after ${ms}ms`)), ms);
+  });
+  return Promise.race([p, timeout]).finally(() => {
+    if (timer !== undefined) clearTimeout(timer);
+  });
+}
+
+Deno.test('express instrumentation: included in default integrations (Deno 2.8.0+)', () => {
+  resetGlobals();
+  const client = init({ dsn: 'https://username@domain/123' }) as DenoClient;
+  const names = client.getOptions().integrations.map(i => i.name);
+  assert(names.includes('Express'), `Express should be in defaults, got ${names.join(', ')}`);
+});
+
+Deno.test('express instrumentation: orchestrion:express:handle channel produces a nested middleware span', async () => {
+  resetGlobals();
+  const sink = transactionSink();
+  init({
+    dsn: 'https://username@domain/123',
+    tracesSampleRate: 1,
+    beforeSendTransaction: sink.beforeSendTransaction,
+  });
+
+  const channel = tracingChannel('orchestrion:express:handle');
+
+  // `self` is the routing layer; `arguments` are `[req, res, next]`. A 3-arg
+  // handler that isn't a router or route-dispatch is traced as a middleware.
+  const layer = { name: 'myMiddleware', handle: (_req: unknown, _res: unknown, _next: unknown) => undefined };
+  const res = new EventEmitter();
+  const ctx = { self: layer, arguments: [{}, res, () => undefined] };
+
+  startSpan({ name: 'parent', op: 'test' }, () => {
+    channel.start.runStores(ctx, () => undefined);
+    channel.asyncStart.runStores(ctx, () => undefined);
+    channel.asyncEnd.publish(ctx);
+  });
+
+  const parent = await withTimeout(
+    sink.waitFor(t => t.transaction === 'parent'),
+    5000,
+    "'parent' transaction",
+  );
+
+  const expressSpan = parent.spans?.find(s => s.op === 'middleware.express');
+  assertExists(expressSpan, `expected a middleware.express span, got ops: ${parent.spans?.map(s => s.op).join(', ')}`);
+  assertEquals(expressSpan!.description, 'myMiddleware');
+  assertEquals(expressSpan!.data?.['express.name'], 'myMiddleware');
+  assertEquals(expressSpan!.data?.['express.type'], 'middleware');
+  assertEquals(expressSpan!.data?.['sentry.origin'], 'auto.http.express');
+});
diff --git a/packages/deno/src/index.ts b/packages/deno/src/index.ts
index 404bdbabb833..7bfba75dbb2e 100644
--- a/packages/deno/src/index.ts
+++ b/packages/deno/src/index.ts
@@ -118,6 +118,7 @@ export type { DenoRedisIntegrationOptions } from './integrations/redis';
 export {
   amqplibChannelIntegration,
   dataloaderChannelIntegration,
+  expressChannelIntegration,
   genericPoolChannelIntegration,
   knexChannelIntegration,
   koaChannelIntegration,
diff --git a/packages/deno/src/sdk.ts b/packages/deno/src/sdk.ts
index 78c85bd29a2c..789dac54d8f4 100644
--- a/packages/deno/src/sdk.ts
+++ b/packages/deno/src/sdk.ts
@@ -13,6 +13,7 @@ import {
 } from '@sentry/core';
 import {
   amqplibChannelIntegration,
+  expressChannelIntegration,
   genericPoolChannelIntegration,
   koaChannelIntegration,
   lruMemoizerChannelIntegration,
@@ -77,6 +78,7 @@ export function getDefaultIntegrations(_options: Options): Integration[] {
     ...(MODULE_REGISTER_HOOKS_SUPPORTED
       ? [
           amqplibChannelIntegration(),
+          expressChannelIntegration(),
           genericPoolChannelIntegration(),
           koaChannelIntegration(),
           lruMemoizerChannelIntegration(),
diff --git a/packages/deno/test/__snapshots__/mod.test.ts.snap b/packages/deno/test/__snapshots__/mod.test.ts.snap
index a0aa2ff47068..cf5455ad9e02 100644
--- a/packages/deno/test/__snapshots__/mod.test.ts.snap
+++ b/packages/deno/test/__snapshots__/mod.test.ts.snap
@@ -116,6 +116,7 @@ snapshot[`captureException 1`] = `
       "DenoHttp",
       "DenoRedis",
       "Amqplib",
+      "Express",
       "GenericPool",
       "Koa",
       "LruMemoizer",
@@ -202,6 +203,7 @@ snapshot[`captureMessage 1`] = `
       "DenoHttp",
       "DenoRedis",
       "Amqplib",
+      "Express",
       "GenericPool",
       "Koa",
       "LruMemoizer",
@@ -295,6 +297,7 @@ snapshot[`captureMessage twice 1`] = `
       "DenoHttp",
       "DenoRedis",
       "Amqplib",
+      "Express",
       "GenericPool",
       "Koa",
       "LruMemoizer",
@@ -395,6 +398,7 @@ snapshot[`captureMessage twice 2`] = `
       "DenoHttp",
       "DenoRedis",
       "Amqplib",
+      "Express",
       "GenericPool",
       "Koa",
       "LruMemoizer",