diff --git a/packages/react-native/Libraries/Pressability/Pressability.js b/packages/react-native/Libraries/Pressability/Pressability.js
index 0be465bec546..ba7d858be895 100644
--- a/packages/react-native/Libraries/Pressability/Pressability.js
+++ b/packages/react-native/Libraries/Pressability/Pressability.js
@@ -385,6 +385,8 @@ export default class Pressability {
     top: number,
   }> = null;
   _touchActivatePosition: ?Readonly<{
+    locationX: number,
+    locationY: number,
     pageX: number,
     pageY: number,
   }>;
@@ -721,6 +723,7 @@ export default class Pressability {
       !isActivationSignal(prevState) && isActivationSignal(nextState);
 
     if (isInitialTransition || isActivationTransition) {
+      this._recordTouchActivatePosition(event);
       this._measureResponderRegion();
     }
 
@@ -764,14 +767,18 @@ export default class Pressability {
 
   _activate(event: GestureResponderEvent): void {
     const {onPressIn} = this._config;
-    const {pageX, pageY} = getTouchFromPressEvent(event);
-    this._touchActivatePosition = {pageX, pageY};
+    this._recordTouchActivatePosition(event);
     this._touchActivateTime = Date.now();
     if (onPressIn != null) {
       onPressIn(event);
     }
   }
 
+  _recordTouchActivatePosition(event: GestureResponderEvent): void {
+    const {locationX, locationY, pageX, pageY} = getTouchFromPressEvent(event);
+    this._touchActivatePosition = {locationX, locationY, pageX, pageY};
+  }
+
   _deactivate(event: GestureResponderEvent): void {
     const {onPressOut} = this._config;
     if (onPressOut != null) {
@@ -820,16 +827,42 @@ export default class Pressability {
     if (!left && !top && !width && !height && !pageX && !pageY) {
       return;
     }
-    this._responderRegion = {
+    const responderRegion = {
       bottom: pageY + height,
       left: pageX,
       right: pageX + width,
       top: pageY,
     };
+
+    const touch = this._touchActivatePosition;
+    if (
+      touch != null &&
+      !this._isTouchWithinResponderRegion(touch, responderRegion)
+    ) {
+      const correctedLeft = touch.pageX - touch.locationX;
+      const correctedTop = touch.pageY - touch.locationY;
+      const correctedRegion = {
+        bottom: correctedTop + height,
+        left: correctedLeft,
+        right: correctedLeft + width,
+        top: correctedTop,
+      };
+
+      if (this._isTouchWithinResponderRegion(touch, correctedRegion)) {
+        this._responderRegion = correctedRegion;
+        return;
+      }
+    }
+
+    this._responderRegion = responderRegion;
   };
 
   _isTouchWithinResponderRegion(
-    touch: GestureResponderEvent['nativeEvent'],
+    touch: Readonly<{
+      pageX: number,
+      pageY: number,
+      ...
+    }>,
     responderRegion: Readonly<{
       bottom: number,
       left: number,
diff --git a/packages/react-native/Libraries/Pressability/__tests__/Pressability-test.js b/packages/react-native/Libraries/Pressability/__tests__/Pressability-test.js
index 05a46d31e9bd..1838e4cf0728 100644
--- a/packages/react-native/Libraries/Pressability/__tests__/Pressability-test.js
+++ b/packages/react-native/Libraries/Pressability/__tests__/Pressability-test.js
@@ -171,11 +171,15 @@ const createMockPressEvent = (
         registrationName: string,
         pageX: number,
         pageY: number,
+        locationX?: number,
+        locationY?: number,
       }>,
 ): GestureResponderEvent => {
   let registrationName = '';
   let pageX = 0;
   let pageY = 0;
+  let locationX = 0;
+  let locationY = 0;
 
   if (typeof nameOrOverrides === 'string') {
     registrationName = nameOrOverrides;
@@ -183,14 +187,19 @@ const createMockPressEvent = (
     registrationName = nameOrOverrides.registrationName;
     pageX = nameOrOverrides.pageX;
     pageY = nameOrOverrides.pageY;
+    locationX = nameOrOverrides.locationX ?? pageX;
+    locationY = nameOrOverrides.locationY ?? pageY;
+  } else {
+    locationX = pageX;
+    locationY = pageY;
   }
 
   const nativeEvent = {
     changedTouches: [] as Array<GestureResponderEvent['nativeEvent']>,
     force: 1,
     identifier: 42,
-    locationX: pageX,
-    locationY: pageY,
+    locationX,
+    locationY,
     pageX,
     pageY,
     target: 42,
@@ -980,6 +989,42 @@ describe('Pressability', () => {
         jest.advanceTimersByTime(630); // 1000 - 500 (onPressIn activation, already advanced before) + DEFAULT_MIN_PRESS_DURATION
         expect(config.onPressOut).toBeCalled();
       });
+
+      it('uses touch location when measured region is shifted from visual position', () => {
+        getMock(UIManager.measure).mockImplementation((id, fn) => {
+          fn(0, 500, mockRegion.width, mockRegion.height, 0, 500);
+        });
+        const {config, handlers} = createMockPressability({
+          delayPressIn: 0,
+        });
+
+        handlers.onStartShouldSetResponder();
+        handlers.onResponderGrant(
+          createMockPressEvent({
+            registrationName: 'onResponderGrant',
+            pageX: 25,
+            pageY: 25,
+            locationX: 25,
+            locationY: 25,
+          }),
+        );
+
+        expect(UIManager.measure).toBeCalled();
+
+        handlers.onResponderMove(
+          createMockPressEvent({
+            registrationName: 'onResponderMove',
+            pageX: 25,
+            pageY: 25,
+            locationX: 25,
+            locationY: 25,
+          }),
+        );
+        handlers.onResponderRelease(createMockPressEvent('onResponderRelease'));
+
+        expect(config.onPressIn).toBeCalled();
+        expect(config.onPress).toBeCalled();
+      });
     });
   });